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1

Fighting the War Against COVID-19 via Cell-Based Regenerative Medicine: Lessons Learned from 1918 Spanish Flu and Other Previous Pandemics

Park, You Jeong, Farooq, Jeffrey, Cho, Justin, Sadanandan, Nadia, Cozene, Blaise, Gonzales-Portillo, Bella, Saft, Madeline, Borlongan, Maximillian C., Borlongan, Mia C., Shytle, R. Douglas, Willing, A

Journal:

Stem Cell Reviews and Reports

Year:

2020

File:

PDF, 1.56 MB

2020

2

Green tea epigallocatechin-3-gallate (EGCG) reduces β-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice

Kavon Rezai-Zadeh, Gary W. Arendash, Huayan Hou, Frank Fernandez, Maren Jensen, Melissa Runfeldt, R. Douglas Shytle, Jun Tan

Journal:

Year:

2008

Language:

english

File:

PDF, 829 KB

english, 2008

3

Nicotine's oxidative and antioxidant properties in CNS

Mary B Newman, Gary W Arendash, R.Douglas Shytle, Paula C Bickford, Thomas Tighe, Paul R Sanberg

Journal:

Year:

2002

Language:

english

File:

PDF, 142 KB

english, 2002

4

Nutraceutical Intervention Improves Older Adults' Cognitive Functioning

Small, Brent J., Rawson, Kerri S., Martin, Christina, Eisel, Sarah L., Sanberg, Cyndy D., McEvoy, Cathy L., Sanberg, Paul R., Shytle, R. Douglas, Tan, Jun, Bickford, Paula C.

Journal:

Rejuvenation Research

Year:

2014

Language:

english

File:

PDF, 212 KB

english, 2014

5

Psychometric Properties of the Hoarding Assessment Scale in College Students

Schneider, Andrea F., Storch, Eric A., Geffken, Gary R., Lack, Caleb W., Shytle, R. Douglas

Journal:

Illness Crisis & Loss

Year:

2008

Language:

english

File:

PDF, 68 KB

english, 2008

6

Anxiolytic effects of mecamylamine in two animal models of anxiety.

Newman, Mary B., Manresa, John J., Sanberg, Paul R., Shytle, R. Douglas

Journal:

Experimental and Clinical Psychopharmacology

Year:

2002

Language:

english

File:

PDF, 379 KB

english, 2002

7

Cocrystals of Quercetin with Improved Solubility and Oral Bioavailability

Smith, Adam J., Kavuru, Padmini, Wojtas, Lukasz, Zaworotko, Michael J., Shytle, R. Douglas

Journal:

Molecular Pharmaceutics

Year:

2011

Language:

english

File:

PDF, 3.69 MB

english, 2011

8

Nicotine for the treatment of Tourette's syndrome

Paul R. Sanberg, Archie A. Silver, R.Doug Shytle, Mary Katherine Philipp, David W. Cahill, Harold M. Fogelson, Brian J. McConville

Journal:

Pharmacology & Therapeutics

Year:

1997

Language:

english

File:

PDF, 711 KB

english, 1997

9

Smoking cessation programmes are neglecting the needs of persons with neuropsychiatric disorders

S. POLGAR, M. McGartland, C. V. BORLONGAN, R. D. SHYTLE, P. R. SANBERG

Journal:

Internal Medicine Journal

Year:

1996

Language:

english

File:

PDF, 130 KB

english, 1996

10

ZIPRASIDONE-INDUCED OCULOGYRIC CRISIS

Ramos, Amaya E., Shytle, R. Douglas, Silver, Archie A., Sanberg, Paul R.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

2003

Language:

english

File:

PDF, 71 KB

english, 2003

11

P4-267

Tan, Jun, Obregon, Demian, Rezai-Zadeh, Kavon, Bai, Yun, Sun, Nan, Hou, Huayan, Zeng, Jin, Mori, Takashi, Arndash, Gary, Shytle, Doug, Town, Terrence

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

12

Lovastatin modulation of microglial activation via suppression of functional CD40 expression

Kirk P. Townsend, Doug R. Shytle, Yun Bai, Nan San, Jin Zeng, Melissa Freeman, Takashi Mori, Francisco Fernandez, David Morgan, Paul Sanberg, Jun Tan

Journal:

Journal of Neuroscience Research

Year:

2004

Language:

english

File:

PDF, 798 KB

english, 2004

13

Comorbid bipolar disorder in Tourette’s syndrome responds to the nicotinic receptor antagonist mecamylamine (Inversine)

R.Douglas Shytle, Archie A Silver, Paul R Sanberg

Journal:

Biological Psychiatry

Year:

2000

Language:

english

File:

PDF, 26 KB

english, 2000

14

Crystal Engineering of Green Tea Epigallocatechin-3-gallate (EGCg) Cocrystals and Pharmacokinetic Modulation in Rats

Smith, Adam J., Kavuru, Padmini, Arora, Kapildev K., Kesani, Sheshanka, Tan, Jun, Zaworotko, Michael J., Shytle, R. Douglas

Journal:

Molecular Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 3.29 MB

english, 2013

15

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage

Nikolic, W. V., Bai, Y., Obregon, D., Hou, H., Mori, T., Zeng, J., Ehrhart, J., Shytle, R. D., Giunta, B., Morgan, D., Town, T., Tan, J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 1.33 MB

english, 2007

16

Mecamylamine Effects on Haloperidol-Induced Catalepsy and Defecation

Sanberg, Paul R., Newman, Mary B., Manresa, John J., Potts, Sarah E., Alvarez, Franco, Cahill, David W., Shytle, R. Douglas

Journal:

International Journal of Neuroscience

Year:

2001

Language:

english

File:

PDF, 544 KB

english, 2001

17

Corticosterone-attenuating and anxiolytic properties of mecamylamine in the rat

Mary B. Newman, Stanley J. Nazian, Paul R. Sanberg, David M. Diamond, R.Douglas Shytle

Journal:

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Year:

2001

Language:

english

File:

PDF, 541 KB

english, 2001

18

Mecamylamine: new therapeutic uses and toxicity/risk profile

John M. Young, R. Douglas Shytle, Paul R. Sanberg, Tony P. George

Journal:

Clinical Therapeutics

Year:

2001

Language:

english

File:

PDF, 2.55 MB

english, 2001

19

Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation

Jared Ehrhart, Demian Obregon, Takashi Mori, Huayan Hou, Nan Sun, Yun Bai, Thomas Klein, Francisco Fernandez, Jun Tan, R Douglas Shytle

Journal:

Journal of Neuroinflammation

Year:

2005

Language:

english

File:

PDF, 1.30 MB

english, 2005

20

Nicotinic acetylcholine receptors on NT2 precursor cells and hNT (NT2-N) neurons

Mary B Newman, Yen-Ping Kuo, Ronald J Lukas, Paul R Sanberg, R Douglas Shytle, Michael P McGrogan, Tanja Zigova

Journal:

Developmental Brain Research

Year:

2002

Language:

english

File:

PDF, 654 KB

english, 2002

21

Nicotine induced seizures blocked by mecamylamine and its stereoisomers

Mary B. Newman, John J. Manresa, Paul R. Sanberg, R.Douglas Shytle

Journal:

Year:

2001

Language:

english

File:

PDF, 161 KB

english, 2001

22

Nicotine Blocks Kainic Acid-Induced Wet Dog Shakes in Rats

Shytle, R Douglas, Borlongan, Cesario V, Sanberg, Paul R

Journal:

Neuropsychopharmacology

Year:

1995

File:

PDF, 284 KB

1995

23

Octyl Gallate Markedly Promotes Anti-Amyloidogenic Processing of APP through Estrogen Receptor-Mediated ADAM10 Activation

Zhang, She-Qing, Sawmiller, Darrell, Li, Song, Rezai-Zadeh, Kavon, Hou, Huayan, Zhou, Shufeng, Shytle, Douglas, Giunta, Brian, Fernandez, Frank, Mori, Takashi, Tan, Jun, Lakshmana, Madepalli K.

Journal:

Year:

2013

Language:

english

File:

PDF, 973 KB

english, 2013

24

Retrospective Case Series of Traumatic Brain Injury and Post-Traumatic Stress Disorder Treated with Hyperbaric Oxygen Therapy

Douglas Shytle, R., Eve, David J., Kim, Soel-Hee, Spiegel, Allan, Sanberg, Paul R., Borlongan, Cesar V.

Journal:

Cell Transplantation

Year:

2019

File:

PDF, 411 KB

2019

25

Family Impact of Tourette's Syndrome

Berney J. Wilkinson, Mary B. Newman, R.Douglas Shytle, Archie A. Silver, Paul R. Sanberg, David Sheehan

Journal:

Journal of Child and Family Studies

Year:

2001

Language:

english

File:

PDF, 26 KB

english, 2001

26

Defining Treatment Response in Pediatric Tic Disorders: A Signal Detection Analysis of the Yale Global Tic Severity Scale

Storch, Eric A., De Nadai, Alessandro S., Lewin, Adam B., McGuire, Joseph F., Jones, Anna M., Mutch, P. Jane, Shytle, R. Doug, Murphy, Tanya K.

Journal:

Journal of Child and Adolescent Psychopharmacology

Year:

2011

Language:

english

File:

PDF, 217 KB

english, 2011

27

Optimized Turmeric Extracts have Potent Anti-Amyloidogenic Effects

Shytle, R., Bickford, Paula, Rezai-zadeh, Kavon, Hou, L., Zeng, Jin, Tan, Jun, Sanberg, Paul, Sanberg, Cyndy, Roschek Jr., Bill, Fink, Ryan, Alberte, Randall

Journal:

Current Alzheimer Research

Year:

2009

Language:

english

File:

PDF, 359 KB

english, 2009

28

Striatal dopamine-mediated motor behavior is altered following occlusion of the middle cerebral artery

Cesario V. Borlongan, Rodrigo Martinez, R.Douglas Shytle, Thomas B. Freeman, David W. Cahill, Paul R. Sanberg

Journal:

Pharmacology Biochemistry and Behavior

Year:

1995

Language:

english

File:

PDF, 543 KB

english, 1995

29

Fish oil enhances anti-amyloidogenic properties of green tea EGCG in Tg2576 mice

Brian Giunta, Houyan Hou, Yuyan Zhu, Jon Salemi, Amanda Ruscin, R. Douglas Shytle, Jun Tan

Journal:

Neuroscience Letters

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

30

P1-418 Lovastatin modulation of microglial activation via suppression of CD40 and its signaling pathway

Kirk P. Townsend, Dough Shytle, Nan Sun, Jin Zeng, Yun Bai, Martina Vendrame, Francisco Fernandez, David Morgan, Paul Sanberg, Jun Tan

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 329 KB

english, 2004

31

Optimized Turmeric Extract Reduces β-Amyloid and Phosphorylated Tau Protein Burden in Alzheimer’s Transgenic Mice

Shytle, R. Douglas, Tan, Jun, C. Bickford, Paula, Rezai-zadeh, Kavon, Hou, L, Zeng, Jin, Sanberg, Paul R., Sanberg, Cyndy D., S. Alberte, Randall, C. Fink, Ryan, Roschek Jr, Bill

Journal:

Current Alzheimer Research

Year:

2012

Language:

english

File:

PDF, 413 KB

english, 2012

32

Beneficial effects of a pyrroloquinolinequinone-containing dietary formulation on motor deficiency, cognitive decline and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

Sawmiller, Darrell, Li, Song, Mori, Takashi, Habib, Ahsan, Rongo, David, Delic, Vedad, Bradshaw, Patrick C., Shytle, R. Douglas, Sanberg, Cyndy, Bickford, Paula, Tan, Jun

Journal:

Year:

2017

Language:

english

File:

PDF, 1.61 MB

english, 2017

33

P1-342 Cholinergic regulation of microglial activation in response to abeta

R. Douglas Shytle, Kirk Townsend, Jared Ehrhart, Nan Sun, Jin Zeng, Paul R. Sanberg, Jun Tan

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 166 KB

english, 2004

34

Case Study: Long-Term Potentiation of Neuroleptics with Transdermal Nicotine in Tourette's Syndrome

SILVER, ARCHIE A., SHYTLE, R DOUGLAS, PHILIPP, MARY K., SANBERG, PAUL R.

Journal:

Journal of the American Academy of Child & Adolescent Psychiatry

Year:

1996

Language:

english

File:

PDF, 4.58 MB

english, 1996

35

Comparing the effect of the novel ionic cocrystal of lithium salicylate proline (LISPRO) with lithium carbonate and lithium salicylate on memory and behavior in female APPswe/PS1dE9 Alzheimer's mice

Habib, Ahsan, Shytle, R. Douglas, Sawmiller, Darrell, Koilraj, Selina, Munna, Sadia Afrin, Rongo, David, Hou, Huayan, Borlongan, Cesario V., Currier, Glenn, Tan, Jun

Journal:

Journal of Neuroscience Research

Year:

2019

Language:

english

File:

PDF, 1.41 MB

english, 2019

36

Nicotinic acetylcholine receptors as targets for antidepressants

Shytle, R D, Silver, A A, Lukas, R J, Newman, M B, Sheehan, D V, Sanberg, P R

Journal:

Molecular Psychiatry

Year:

2002

Language:

english

File:

PDF, 168 KB

english, 2002

37

EGCG mitigates neurotoxicity mediated by HIV-1 proteins gp120 and Tat in the presence of IFN-γ: Role of JAK/STAT1 signaling and implications for HIV-associated dementia

Brian Giunta, Demian Obregon, Hauyan Hou, Jin Zeng, Nan Sun, Veljko Nikolic, Jared Ehrhart, Douglas Shytle, Francisco Fernandez, Jun Tan

Journal:

Year:

2006

Language:

english

File:

PDF, 848 KB

english, 2006

38

Flavonoid-mediated presenilin-1 phosphorylation reduces Alzheimer's disease β-amyloid production

Kavon Rezai-Zadeh, R. Douglas Shytle, Yun Bai, Jun Tian, Huayan Hou, Takashi Mori, Jin Zeng, Demian Obregon, Terrence Town, Jun Tan

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

39

Mecamylamine – a nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders

Bacher, Ingrid, Wu, Becky, Shytle, Douglas R, George, Tony P

Journal:

Expert Opinion on Pharmacotherapy

Year:

2009

Language:

english

File:

PDF, 339 KB

english, 2009

40

ADAM10 Activation Is Required for Green Tea (-)-Epigallocatechin-3-gallate-induced -Secretase Cleavage of Amyloid Precursor Protein

Obregon, D. F., Rezai-Zadeh, K., Bai, Y., Sun, N., Hou, H., Ehrhart, J., Zeng, J., Mori, T., Arendash, G. W., Shytle, D., Town, T., Tan, J.

Journal:

Journal of Biological Chemistry

Year:

2006

Language:

english

File:

PDF, 661 KB

english, 2006

41

Addressing potential role of magnesium dyshomeostasis to improve treatment efficacy for epilepsy: A reexamination of the literature

Osborn, Katie E., Shytle, R. Douglas, Frontera, Alfred T., Soble, Jason R., Schoenberg, Mike R.

Journal:

Journal of Clinical Pharmacology

Year:

2016

Language:

english

File:

PDF, 163 KB

english, 2016

42

Clinical Experience With Transdermal Nicotine Patch in Tourette Syndrome

Silver, Archie A., Shytle, R. Douglas, Sanberg, Paul R.

Journal:

Year:

1999

Language:

english

File:

PDF, 14.64 MB

english, 1999

43

Transdermal nicotine for Tourette's syndrome

R. Doug Shytle, Archie A. Silver, Mary Katherine Philipp, Brian J. McConville, Paul R. Sanberg

Journal:

Drug Development Research

Year:

1996

Language:

english

File:

PDF, 956 KB

english, 1996

44

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

Kavon Rezai-Zadeh, Jared Ehrhart, Yun Bai, Paul R Sanberg, Paula Bickford, Jun Tan, R Douglas Shytle

Journal:

Journal of Neuroinflammation

Year:

2008

Language:

english

File:

PDF, 344 KB

english, 2008

45

P3-410 Regulation of the innate and adaptive activation of microglia in responses to Aβ by CD40 signaling

Tan, Jun, Townsend, Kirk, Lue, Lih-Fen, Sun, Nan, Zeng, Jin, Mori, Takashi, Shytle, Doug, Morgan, David, Town, Terrence

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 164 KB

english, 2004

46

Humoral factors in ALS patients during disease progression

Ehrhart, Jared, Smith, Adam J., Kuzmin-Nichols, Nicole, Zesiewicz, Theresa A., Jahan, Israt, Shytle, R. Douglas, Kim, Seol-Hee, Sanberg, Cyndy D., Vu, Tuan H., Gooch, Clifton L., Sanberg, Paul R., Gar

Journal:

Journal of Neuroinflammation

Year:

2015

Language:

english

File:

PDF, 717 KB

english, 2015

47

Plasma and brain pharmacokinetics of previously unexplored lithium salts

Smith, Adam J., Kim, Seol-Hee, Tan, Jun, Sneed, Kevin B., Sanberg, Paul R., Borlongan, Cesar V., Shytle, R. Douglas

Journal:

Year:

2014

Language:

english

File:

PDF, 289 KB

english, 2014

48

Oxidative Stress of Neural, Hematopoietic, and Stem Cells: Protection by Natural Compounds

Shytle, R. Douglas, Ehrhart, Jared, Tan, Jun, Vila, Jennifer, Cole, Michael, Sanberg, Cyndy D., Sanberg, Paul R., Bickford, Paula C.

Journal:

Rejuvenation Research

Year:

2007

Language:

english

File:

PDF, 2.81 MB

english, 2007

49

Clinical Experience With Transdermal Nicotine Patch in Tourette Syndrome

Silver, Archie A., Shytle, R. Douglas, Sanberg, Paul R.

Journal:

Year:

1999

File:

PDF, 14.64 MB

1999

50

CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid β-peptide

Kirk P. Townsend, Terrence Town, Takashi Mori, Lih-Fen Lue, Doug Shytle, Paul R. Sanberg, David Morgan, Francisco Fernandez, Richard A. Flavell, Jun Tan

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 289 KB

english, 2005

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